Transmission Imaging in Lymphoscintigraphy with a 153Gd Flood Source.
Identifieur interne : 001675 ( Main/Exploration ); précédent : 001674; suivant : 001676Transmission Imaging in Lymphoscintigraphy with a 153Gd Flood Source.
Auteurs : Frank P. Difilippo [République centrafricaine] ; Richard C. Brunken [États-Unis] ; Donald R. Neumann [États-Unis]Source :
- Journal of nuclear medicine technology [ 1535-5675 ] ; 2015.
Descripteurs français
- KwdFr :
- MESH :
- imagerie diagnostique : Lymphoedème, Région mammaire.
- Artéfacts, Fantômes en imagerie, Gadolinium, Humains, Lymphoscintigraphie, Radio-isotopes, Rapport signal-bruit, Traitement d'image par ordinateur.
English descriptors
- KwdEn :
- MESH :
- chemical : Gadolinium, Radioisotopes.
- diagnostic imaging : Breast, Lymphedema.
- methods : Lymphoscintigraphy.
- Artifacts, Humans, Image Processing, Computer-Assisted, Phantoms, Imaging, Signal-To-Noise Ratio.
Abstract
Lymphoscintigraphy uses intradermal or interstitial injections of (99m)Tc-labeled tracers to produce images of focal lymph nodes. Because there is little or no anatomic information in the (99m)Tc images, a (57)Co flood source is sometimes used to provide transmission data along with the emission data. The anatomic shadow from the transmission scan generally improves interpretation and surgical planning. However, the (57)Co transmission photons contribute to background on the (99m)Tc images, reducing contrast and signal-to-noise ratio (SNR). SNR is related to lesion detection, and some lymph nodes that would be detected in an emission-only scan might not be detected if acquired with a (57)Co flood source. An alternative to a (57)Co flood source is a (153)Gd flood source, which has primary photon emissions well below the (99m)Tc emission window, allowing the shadow to be acquired in a separate transmission window. Significantly smaller crosstalk from (153)Gd should improve SNR and therefore would be expected to improve lymph node detection. We hypothesized that the use of a (153)Gd flood source would reduce background and improve SNR for these studies.
DOI: 10.2967/jnmt.115.161935
PubMed: 26338486
Affiliations:
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Brunken</name><affiliation wicri:level="2"><nlm:affiliation>Department of Nuclear Medicine, Cleveland Clinic, Cleveland, Ohio.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea>Department of Nuclear Medicine, Cleveland Clinic, Cleveland</wicri:cityArea></affiliation></author><author><name sortKey="Neumann, Donald R" sort="Neumann, Donald R" uniqKey="Neumann D" first="Donald R" last="Neumann">Donald R. 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Difilippo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Nuclear Medicine, Cleveland Clinic, Cleveland, Ohio difilif@ccf.org.</nlm:affiliation><country wicri:rule="url">République centrafricaine</country><wicri:regionArea>Department of Nuclear Medicine, Cleveland Clinic, Cleveland</wicri:regionArea><wicri:noRegion>Cleveland</wicri:noRegion></affiliation></author><author><name sortKey="Brunken, Richard C" sort="Brunken, Richard C" uniqKey="Brunken R" first="Richard C" last="Brunken">Richard C. Brunken</name><affiliation wicri:level="2"><nlm:affiliation>Department of Nuclear Medicine, Cleveland Clinic, Cleveland, Ohio.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea>Department of Nuclear Medicine, Cleveland Clinic, Cleveland</wicri:cityArea></affiliation></author><author><name sortKey="Neumann, Donald R" sort="Neumann, Donald R" uniqKey="Neumann D" first="Donald R" last="Neumann">Donald R. Neumann</name><affiliation wicri:level="2"><nlm:affiliation>Department of Nuclear Medicine, Cleveland Clinic, Cleveland, Ohio.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea>Department of Nuclear Medicine, Cleveland Clinic, Cleveland</wicri:cityArea></affiliation></author></analytic><series><title level="j">Journal of nuclear medicine technology</title><idno type="eISSN">1535-5675</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Artifacts</term><term>Breast (diagnostic imaging)</term><term>Gadolinium</term><term>Humans</term><term>Image Processing, Computer-Assisted</term><term>Lymphedema (diagnostic imaging)</term><term>Lymphoscintigraphy (methods)</term><term>Phantoms, Imaging</term><term>Radioisotopes</term><term>Signal-To-Noise Ratio</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Artéfacts</term><term>Fantômes en imagerie</term><term>Gadolinium</term><term>Humains</term><term>Lymphoedème (imagerie diagnostique)</term><term>Lymphoscintigraphie ()</term><term>Radio-isotopes</term><term>Rapport signal-bruit</term><term>Région mammaire (imagerie diagnostique)</term><term>Traitement d'image par ordinateur</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Gadolinium</term><term>Radioisotopes</term></keywords><keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Breast</term><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="imagerie diagnostique" xml:lang="fr"><term>Lymphoedème</term><term>Région mammaire</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Lymphoscintigraphy</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Artifacts</term><term>Humans</term><term>Image Processing, Computer-Assisted</term><term>Phantoms, Imaging</term><term>Signal-To-Noise Ratio</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Artéfacts</term><term>Fantômes en imagerie</term><term>Gadolinium</term><term>Humains</term><term>Lymphoscintigraphie</term><term>Radio-isotopes</term><term>Rapport signal-bruit</term><term>Traitement d'image par ordinateur</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Lymphoscintigraphy uses intradermal or interstitial injections of (99m)Tc-labeled tracers to produce images of focal lymph nodes. Because there is little or no anatomic information in the (99m)Tc images, a (57)Co flood source is sometimes used to provide transmission data along with the emission data. The anatomic shadow from the transmission scan generally improves interpretation and surgical planning. However, the (57)Co transmission photons contribute to background on the (99m)Tc images, reducing contrast and signal-to-noise ratio (SNR). SNR is related to lesion detection, and some lymph nodes that would be detected in an emission-only scan might not be detected if acquired with a (57)Co flood source. An alternative to a (57)Co flood source is a (153)Gd flood source, which has primary photon emissions well below the (99m)Tc emission window, allowing the shadow to be acquired in a separate transmission window. Significantly smaller crosstalk from (153)Gd should improve SNR and therefore would be expected to improve lymph node detection. We hypothesized that the use of a (153)Gd flood source would reduce background and improve SNR for these studies.</div></front></TEI><affiliations><list><country><li>République centrafricaine</li><li>États-Unis</li></country><region><li>Ohio</li></region></list><tree><country name="République centrafricaine"><noRegion><name sortKey="Difilippo, Frank P" sort="Difilippo, Frank P" uniqKey="Difilippo F" first="Frank P" last="Difilippo">Frank P. Difilippo</name></noRegion></country><country name="États-Unis"><region name="Ohio"><name sortKey="Brunken, Richard C" sort="Brunken, Richard C" uniqKey="Brunken R" first="Richard C" last="Brunken">Richard C. Brunken</name></region><name sortKey="Neumann, Donald R" sort="Neumann, Donald R" uniqKey="Neumann D" first="Donald R" last="Neumann">Donald R. Neumann</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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